Study Shows Healthy Arteries May be Possible with Aging

Having the blood vessels of a healthy 20-year-old into one’s 70s is possible but difficult in Western culture, according to new research in the American Heart Association’s journal Hypertension.

“For the most part, it’s not genetic factors that stiffen the body’s network of blood vessels during aging. Modifiable lifestyle factors – like those identified in the American Heart Association’s Life’s Simple 7 –  are the leading culprits,” said study author Teemu J. Niiranen, MD, research fellow at the Framingham Heart Study.

“Vascular aging is thought of as normal aging. As people get older, their arteries become stiffer and they develop high blood pressure. In fact, that’s what happens to most people beyond age 70. But it doesn’t have to happen,” Niiranen said.

Niiranen and colleagues studied 3,196 adults ages 50 and older from the Framingham Heart Study. They defined healthy vascular aging for people 50 years old or older as having both normal blood pressure and pulse-wave velocity near the level of healthy people age 30 or younger. Pulse-wave velocity is a measurement of stiffness in the blood vessels.

Researchers found that overall, 566 (17.7 percent) of the participants studied had healthy vascular aging. The group most likely to have healthy vascular aging was the youngest. More than 30 percent of those 50 to 59 years old in the sample met the standards for healthy vascular aging. Only one percent of those 70 and older had healthy vascular aging, and they were more likely to be women.

The most important factors of achieving healthy vascular function were staying lean, or having a low body mass index, and avoiding diabetes, according to Niiranen.

The study co-authors are Asya Lyass, PhD; Martin G. Larson, SD; Naomi M. Hamburg, MD, MS; Emelia J. Benjamin, MD, ScM; Gary F. Mitchell, MD; and Ramachandran S. Vasan, MD.