Head & Neck

Head & Neck Squamous Cell Carcinoma

CIRB #H-32379/ RTOG #R1216: Randomized Phase II/III Trial of Adjuvant Radiation Therapy with Cisplatin, Docetaxel-Cetuximab, or Cisplatin-Atezolizumab in Pathologic High-Risk Squamous Cell Cancer of the Head and Neck

CIRB # H-41338/ NRG #HN006: Randomized Phase II/III Trial of Sentinel Lymph Node Biopsy Versus Elective Neck Dissection for Early-Stage Oral Cavity Cancer

CIRB # H-39827/ NRG #HN005: Randomized Phase II/III Trial of De-Intensified Radiation Therapy for Patients with Early-Stage, p16-Positive, Non-Smoking Associated Oropharyngeal Cancer (temporary closure)

IRB #H-38134/ RTOG Foundation #R3507 (KEYSTROKE): A Randomized phase II study of Pembrolizumab (KEYTRUDA®) plus STeReOtactic Re-Irradiation versus SBRT alone for Locoregionally Recurrent or Second Primary Head and NEcK Carcinoma

Nasopharyngeal

IRB #H-45017/ RTOG Foundation #CHS-007-01/RTOG 3521 (TRANSPARENT): Single-Arm Study of Toripalimab in Combination with Cisplatin and Gemcitabine in Recurrent Metastatic Nasopharyngeal Carcinoma Systemic Treatment Naïve Participants (pending IRB)